1. The Musical Chairs Syndrome

Changes abound at MIB as Dr. Zeeltor takes over in the lab for Elle, who has become a field agent and gotten partnered with an alien named Agent X. As these new changes set in, MIB has to stop New York from being devoured by a Barooga.

2. The Spectacle Syndrome

Jay and Kay have to rescue the worms from an alien world similar to Ancient Rome.

3. The Back to School Syndrome

Jay poses as a high school student to protect an alien prince from alien terrorists.

4. The Opening Gambit Syndrome

Thirty years ago, an Ixion named Vangus came to Earth and was stopped by an MIB agent. Now when Vangus returns, MIB seeks answers from the agent that stopped him: Alpha.

5. The Future's So Bright Syndrome

During pursuit of a large criminal Worm, Jay gets sent to the future and finds that the Worms rule all of Earth.

6. The Loose Ball Foul Syndrome

The Fmeks are back and trying to take over a tiny planet that resembles a baseball. To make matters worse, Kay is on the tiny planet and things are getting very hot.

7. The Hots for Jay Syndrome

After eating some alien food, Jay gains the ability to throw fire. But this new power will have serious consequences if he keeps using it.

8. The Circus Parade Syndrome

A member of a witness protection program for aliens is on the run from an intergalatic gang called The Association when they discover he's on Earth.

9. The Virtual Crossfire Syndrome

Jay gets a low score on MIB's new virtual reality training test and the embarassment eventually forces him to try again. But this time the game goes haywire and the dangers Jay faces become deadly.

10. The Breaking News Syndrome

An alien tv crew comes to Earth to film MIB agents on the job just as Drekk returns to cause trouble.

11. The Zero to Superhero Syndrome

A super hero caling himself Cosmosis emerges to defend the city from evil, but he's really an alien looking to put his powers to good use. However, MIB feels his new profession could attract trouble for Earth, so they try to lure him out using Jay as bait.

13. The Endgame Syndrome, Part 2

With MIB having success in coordinating resistance against the invasion, the Ixions plan to unleash a weapon that will kill everyone on Earth. Jay and Kay will fight Alpha in the final battle for humanity.